Date: 19 December 2021
Venue: La Seine Musicale (Paris, France)
Voting system: 1-8, 10 & 12 points. Jury + Televoting 50%
Number of countries: 19
Hosts:
Slogan: Imagine
Scoreboard:
Participants
| Country | Performer | Song | Points | Place | ||
| 1 |  | Germany | Pauline | Imagine Us | 61 | 17 |
| 2 |  | Georgia | Niko Kajaia | Let’s Count The Smiles | 163 | 4 |
| 3 |  | Poland | Sara James | Somebody | 218 | 2 |
| 4 |  | Malta | Ike & Kaya | My Home | 97 | 12 |
| 5 |  | Italy | Elisabetta Lizza | Specchio (Mirror On The Wall) | 107 | 10 |
| 6 |  | Bulgaria | Denislava & Martin | Voice Of Love | 77 | 16 |
| 7 |  | Russia | Tanya Mezhentseva | Mon Ami | 124 | 7 |
| 8 |  | Ireland | Maiú Levi Lawlor | Saor (Disappear) | 44 | 18 |
| 9 |  | Armenia | Maléna | Qami Qami | 224 | 1 |
| 10 |  | Kazakhstan | Alinur Khamzin & Beknur Zhanibekuly | Ертегі әлемі (Fairy World) | 121 | 8 |
| 11 |  | Albania | Anna Gjebrea | Stand By You | 84 | 14 |
| 12 |  | Ukraine | Olena Usenko | Vazhil | 125 | 6 |
| 13 |  | France | Enzo | Tic Tac | 187 | 3 |
| 14 |  | Azerbaijan | Sona Azizova | One Of Those Days | 151 | 5 |
| 15 |  | The Netherlands | Ayana | Mata Sugu Aō Ne | 43 | 19 |
| 16 |  | Spain | Levi Díaz | Reír | 77 | 15 |
| 17 |  | Serbia | Jovana & Dunja | Oči Deteta (Children’s Eyes) | 86 | 13 |
| 18 |  | North Macedonia | Dajte Muzika | Green Forces | 114 | 9 |
| 19 |  | Portugal | Simão Oliveira | O Rapaz | 101 | 11 |
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